H.S. Guide A-Z 2021 - Réglementation References : (Art 13.5), higher risks of negative opi- A failure to stimulate nions, complex foods, phytonutrients, innovation Askew K (2020), https:// www.foodnavigator. lipids and physiological functions inclu- The aim of the European Regulation com/Article/2020/11/11/ 1924/2006 was to protect consumers from EU-health-claims-are- ding weight management, urinary health, failing-consumers-and- antioxidant properties, skin and sex- pseudo-scientific arguments, to harmonize manufacturers-The- regulation-is-not-working dependent functions. These are topics for practices within the European Union, and DGCCRF (2018), https:// which the choice of functional marker and to promote food innovation. It is clear from www.economie.gouv. fr/dgccrf/controle-des- the title of the claim are more complex. In the analysis of these 296 opinions that this allegations-nutritionnelles- et-sante addition, functional claims are more dif- is rather a failure on some points. The ana- Flynn A (2012), Scientificficult to validate because clinical studies lysis of scientific records by the experts substantiation of health claims in the must demonstrate the ability to maintain of the NDA panel is based solely on the EU. Proceedings of the normal physiological functions. Finally, the recognition of randomized, controlled and Nutrition Society, 71(1): p120-126 more complex the product, the more dif- double-blind studies. Although this is the Foe M & Younes H (2016), ficult it is to find in the literature quality “gold standard” for clinical studies in the Elaboration d’un dossier de demande d’autorisation and relevant clinical studies to support the pharmaceutical world, these constraints d’une allégation santé. Comment répondre aux physiological effect sought. can be difficult to apply in the world of exigences des experts de l’EFSA? Actifs H.S. “AZ Guide 2016” p88-103 034 FIGURE 5: Graphic representation of cluster analysis of the relationship between the type of claim, the active ingredient category, the targeted function and the type of product Analysis by the RStudio software and projection of individuals on axes 1 and 2. Profiles 1 to 5 are described in the main document ■ / A - Z Ingrédients Santé 2021 / Hors-Série / L’Actualité des Ingrédients Fonctionnels & Santé