Industry \ Partners - N°64 same is valid where quality is bring forward fl awless delive- directly above the different stalls Key data concerned. “Each of our sites ries. Because “the level of the situated on the ground fl oor. It is is autonowishes to accentuate, becausemous, Luc Ardouvinservice and the conformity arekey to this nishing business”.in these stalls that capsules andtablets are produced, as well as 1994 creation of Herbarom in this manner we avoid a This spurs the importance of the powders packaged in sticks Laboratoire – pyramidal structure that is dif- having a production site com- and bags. extraction botanical cult to manage”. This led to pliant with the GMP pharma- Several capsule machines are actives the creation of a network of ceutical norms. placed in each stall – one of 2013 autonomous sites, where the them has a production capacity employees are empowered A GMP of 80,000 capsules/hour. The creation of Phytéo Laboratoire – liquid and therefore involved – again Pharmaceutical site same goes for the tablets – a nutraceticals the human dimension. “My role total of six presses. subcontractor is to have my head up into the From its past as a pharmaceu- The latter are commercialized wind, feel the evolution of the tical laboratory (former Rhône plain, laminated, or coated. 2015 market, and boost the energy”, Poulenc, having been taken “The know-how we had in acquisition of confi des Luc Ardouvin before over by a private investor then coating has turned into a the Pharméal Laboratoires site – dry adding: “we have been able to becoming Pharméal after being technical know-howfrlamio - pharmaceutical- recover the production site and taken over by Novéal, and until nating”, emphasizes Benjamin nutraceutical the one for the packaging of the liquidation of the latter), Derouet, pharmacist in charge products liquid forms, precisely because the site of Phytéo next to Tours and responsible with the deve- 2018 the one of Pharméal was auto- has kept the soul. Exclusively lopment. nomous. This allowed us to dedicated to dry forms, the site The packaging is done on three acquisition of the “liquid” department – release the energy necessary regroups two activities: the pro- blister lines and one pillbox line GMP certifi ed site of for the integration of this site”. duction and packaging of food – always with the same hygiene PiLeJe Industrie supplements on the one hand, rules as the production area. The price of the development and manu- Why produce food supplements non-quality facturing of generic and ori- according to the pharmaceu- 091 ginal medicines on the other tical rules? “It is only logical, What opinion does Luc hand. In fact, the site is GMP states Benjamin Derouet, phar- Ardouvin have in fact on this Pharmaceutical certifi ed. The macist in charge of the site, business of subcontracting? production is done in facilities since the achievement of one Lucid, he observes that “it is complying to pharmaceutical and the other reveals the same a ‘poor’ business where the standards and spreading on constraints – not only regula- margins arelow”. Whence the two fl oors. The central corridor tion-wise”. Having nutraceu- importance of achieving not running along the entire buil- tical products in a GMP envi- only the economies of scale, ding is pressurised to avoid ronment has a certain price. but also (and more importantly) cross-contamination. Concerning production itself, delivering quality. “The pres- The two weighing stalls are but also the quality. Thus, “a sure of the non-quality is very under laminar flow. Once new raw material, whether strong because it has a price received, the range of ingre- referenced by us or brought by that the client can assess. Just dients are taken upstairs so our clients, undergoes almost as they can evaluate the cost that the raw materials could be the same validation process, of the delays in the nishing of granulated or not according whether it is destined for the a production”. Another obser- to the needs: “a largely used pharmaceuticals or nutraceu- vation: the contractors tend to procedure in the pharmaceu- ticals”. The same happens for concentrate more and more – tical industry, mainly because the process control: a food sup- according to the repurchases/ it operates with highly dosed plement in the form of a tablet take-overs/fusions of the last products and hard to press undergoes the same batch of years – “it is obvious that we materials”. tests as a medicine. “Our job need also to be able to accom- The two granulation boxes requires extreme exigency”, pany them inthis movement of (adding water and a caking concludes Luc Ardouvin. “We concentration”. In this respect, agent) under fl uidised beds are are developing because we are “technical expertise is not suf- equipped with Glatt (120 and a company of projects that we cient in itself”. What is in fact, 200) material. The containers of approach with pragmatism and is to reach a critical size and the calibrated powders are taken in a simple and ef cient way”.■ News on Functional & Health Ingredients \ N°64 \ July - August - September 2018 \ ■