N°64 - Marché / Articulation-os (40 mg/day). It seems to be able to involve the immune system in the process of repairing the PLANT-SOURCED CALCIUM connective tissue. Rousselot has developed a new grade of Vidya offers Nutrisea, an extract that contains Peptan® IIm collagen: a hydrolysed cartilage 13% calcium obtained via aqueous extraction matrix containing hydrolysed collagen type from sesame seed hulls grown in southern II in the form of peptides and bioactive gly- India. It is supported by the Full ID™ total cosaminoglycans (chondroitin and hyaluronic traceability internal certification system. acid). Its effectiveness has been shown via This calcium is naturally bioavailable at in vivo studies: protection against cartilage 65%. Its concentrated form has fewer anti- degeneration, anti-infl ammatory action (post- nutritional compounds. It allows providing traumatic osteoarthritis or associated with consumers with food intolerance or specific obesity), protection against synovial infl am- food choices (vegetarianism or veganism) the calcium their organism needs. mation. Highly bioavailable, Peptan® IIm is active at a low dosage (between 1 and 3g/d), which opens the doors to food supplement applications. On the side of conventional ingredients, such as glucosamine, chondroitin, the most notable Other ingredients - more than thirty in total news is their transition to “greens”. Via plant - make up a second line: botanical extracts, sourcing, such as ChondroSea® by Pharma- bamboo (silica content), nettle, willow (its bark nager Ingredients or Phytodroitin® by Pro- is known to bring relief to headaches; salicylic TecNutra. Or their fermentation origin, such acid is extracted from it). Among the active as Mythocondro® by Gnosis. molecules, there is astaxanthin (due to its It’s been a few years since market players 036 antioxidant activity), eggshell membrane and have started a real “fi ght” around the key to elastin (glycosaminoglycans), MSM (methyl- its applications: bioavailability. Amongst the sulfonylmethane or DMSO 2 (dimethyl sulfone) most notable recent launches, Hydrocurc®, a or methanesulfonyl chloride which, thanks to water-soluble and water-dispersible curcumin the sulphur it contains, contributes to the pre- launched by Pharmako Biotechnologies (start- servation of the immune functions and the up award). Please note that Indena Group maintenance of connective tissues (tendons, has launched a new label based on Meriva® deep dermis, collagen, cartilage, etc.) in a good (curcumin phytosomes), The Life Guardian™. state. Minerals are also part of this combination Nutris (Acerchem Group) offers a highly bioa- of ingredients. Their presence is explained by vailable grade of turmeric extract marketed the fact that they qualify for Article 13.1 claims under the trade name Cursol®. concerning “the maintenance of bone health”. Innexus Nutraceuticals (The Netherlands) Very often, the equation joints = bone is a must launches OptiPEA®, a palmitoylethanolamide for formulators, which blurs the positioning of extracted from palmitic acid (patented produc- products in consumers’ minds. tion process) with a large number of protective The same goes for the United States: the for- effects for the body (analgesic, anti-infl amma- mulas of food supplements for joint health are tory). very concentrated. With a clear predominance Finally, new active ingredients are emerging! of the glucosamine-chondroitin couple (see Move!plx by Monteloeder, an extract from table). lemon verbena with very high polyphenol levels (phenylpropanoids). Studies have shown the Classic formulas updated capacity of this active ingredient to reduce oxidative stress levels, while also maximizing Continuing to offer classic formulas does not the antioxidant effects and acting on the pro- prevent innovation. Let’s take collagen, for ins- infl ammatory markers (in particular in the knee tance. Lonza has launched UC-II®, an unde- area). natured type II collagen described as having As for Aurea® Biolabs, it proposes Acujoint®, the capacity to maintain and repair cartilage. a combination based on turmeric, boswellia, This patented collagen is used at a low dose pepper and camphor tree extract. The product ■ / Juillet - Août - Septembre 2018 / N°64 / L’Actualité des Ingrédients Fonctionnels & Santé