Exposome / ExposomeTECHNICAL ARTICLE 221 également de bons candidats (12) les contraintes auxquelles sont soumis References . Parmi les terpénoïdes naturels, Green- les cheveux et le cuir chevelu. ■ tech a identifié le Picroside II, un glyco- (1)Wild CP (2005). Cancer Epidemiol Biomarkers Prev, side iridoïde, comme une molécule Rebecca BOUTIN 14: 1847–1850. très intéressante pour limiter la dépig- Ingénieure R&D (2)Miller GW, Jones DP. (2014). Toxicol Sci, 137: 1–2. mentation des cheveux. Arcolys® R&D Engineer (3)Garg S, Sangwan A (2019). Indian Dermatol Online a été développé (Figure 4). En utilisant Carine BOUTOT J. 10:115-124. une approche psychophysiologique, Ingénieure R&D (4)Spencer DK (1998). The hormonal effects of diet on cet ingrédient permet aux cheveux R&D Engineer hair loss. In: Spencer DK, editor. The Bald Truth. New York: Simon and Schuster Inc; pp. 37–54 de retrouver couleur, santé et beauté. Magalie CABANNES (2018). Cosmetics 5, 17. (5)Qu X, et al Dans le même temps, l’estime de soi Responsable du Laboratoire et les émotions positives augmentent. (6)Maeda, K., et al. (2018). Cosmetics 5, 24. d’Application (7)Shacter E (2000). In Methods in Enzymology, Ainsi, le concept d’exposome capillaire Application Laboratory Manager (Elsevier), 428–436. aborde les troubles capillaires dans une perspective innovante, en analy- Jean-Yves BERTHON (8)Fernández, E., et al. (2012a). J. Photochem. sant les influences sur la santé des PDG Photobiol. B 117, 146–156. CEO (9)Krutmann J, et al(2017). 85, 152-161. cheveux de manière holistique, au lieu de traiter indépendamment les signes Edith FILAIRE (10)Chen Y, et al. (2013). Adv. Mater. Res. 821–822, Directrice scientifique 28–31. de dommages capillaires comme cela (11) t a (2019). J. Photochem. Photobiol. B a été fait jusqu’à présent. Le concept Group Scientific Director Chen F, e l 197, 111518. d’exposome vise à ouvrir de nouvelles GREENTECH (12)Niu C, Aisa HA (2017). Molecules 22, 1303. opportunités pour développer des (13)Trüeb RM (2015). Curr Probl Dermatol. 47:107-20. solutions dynamiques et globales contre UNE APPROCHEFIGURE 4 Ex PSYCHOBIOLOGIQUE DU TRAITEMENT DES CHEVEUX GRIS AVEC UN EXTRAIT DE PICRORHIZA SCROPHULARIIFLORA TITRÉ EN PRICOSIDE II. A PSYCHOBIOLOGICAL APPROACH OF HAIR GRAYING TREATMENT WITH A PRICOSIDE II TITRATED PICRORHIZA SCROPHULARIIFLORA EXTRACT. the penetration to the heart of the hair, to stimulate melanogenesis pathways in the hair to regain health and beauty. At it protects the integrity of hair protein melanocyte cell models. Resveratrol and the same time, self-esteem and positive structure, acts against carbonylation and terpenoids have also been identified as emotions are increased. To summarize, limit keratin alteration. Hair is stronger potential up-regulators of melanogenesis hair exposome concept addresses hair and shinier. process (12). Among natural terpenoids, disorders from an innovative perspective, Greentech identified the active compo- analyzing the influences on hair health •Repigmentation of the hair for better nent Picroside II, an iridoid glycoside, holistically, instead of treating signs of self-esteem as a remarkably interesting candidate hair damage independently as it has been Finally, several natural molecules have to target physiological process identi- done hitherto. demonstrated interesting properties fied as contributors of the gradual loss Generally speaking, this concept aims through their pro-melanogenic activity. of hair pigmentation.Thus, Arcolys® to open new opportunities to develop For example, flavonoids (such as narin- was developed (Figure 4). By using a dynamic and global solutions against the genin) and flavonoids glycosides (such psychophysiological approach, it was stresses to which the hair and scalp are as quercetin glucosides) have been shown highlighted that our ingredient enables subjected. ■ The global information on cosmetics & fragrances Guide of cosmetic ingredients - 2020