Slow/Modified Release Vitamin C – An innovative approach Under the name "Slow/Modified Release", Nutriventia hasAlthough Vitamin C cannot be produced by the human body developed a process by which most ingredients for dietaryitself, it performs a large number of tasks that are essential supplements can be carefully adjusted to different releasefor maintaining health and physiological functions. Para- patterns. This allows the number of doses to be reduced, amount in this regard is the immune defense, which cannot be purchasing factor that is especially important for older people.maintained by the body without a sufficient supply of vitamin At the same time, their bioactivity is increased due to theC. In the meantime, science has discovered that the human controlled release. This has a positive effect on the amountbody rapidly degrades vitamin C and excretes it via the kid- of active ingredient required, which can therefore be lowerneys. Thus, the half-life of the plasma level of vitamin C is and thus more sustainable. Slow/modified release thus oftengenerally only about two hours. It follows that a constant makes it much easier to implement many of the legislator'splasma level of vitamin C is a prerequisite for this important rules (compliance). vitamin to be fully effective. Nutriventia has therefore deve- loped C-Fence, a sustained-release product that ensures that® a total amount of 500 mg of vitamin C is made available to Example melatonin the body over a period of 24 hours. This is exactly the amount Melatonin is a hormone that in healthy people is producedconsidered to be optimal in order to permanently maintain the primarily in the pineal gland, a part of the diencephalon, butplasma level of vitamin C. It has now been scientifically con- also in the intestines and in the retina of the eye. It coordinates firmed that one C-Fence tablet provides a full protection for the circadian-rhythmic processes in the body, thus unfolding24 hours. Proper use of caffeine Almost all people encounter a situation where they need to C-Fence® be wide awake. This means athletes,chess players and 100 gamers, but also people on a holiday trip. In such situations, 80 many people turn to highly caffeinated drinks (energy drinks) 60 or consume pure caffeine in tablet or capsule form. Often they 40 are surprised when they are more tired than ever after a short 20 time, because the effect of caffeine increases quickly and de- 0 creases just as quickly. Nutriventia has therefore developed 0 2 4 6 8 1012141618 2022 24 Time in hours CaffXtend, a raw material that can be processed into tablets,® C-Fence Placebo capsules or powder. The product consists of natural caffeine, whose effect is "Slow/Modified".The body thus always receives the amount of caffeine it needs to stay awake without harming health. Vivatis Pharma in Hamburg is the exclusive Fig. 2/ New study shows the C-Fence® optimal Vitamin C plasma concentration over 24 hours. CaffXtend® its effect as a timing agent or fatigue inducer. Together with 100 adenosine, another endogenous hormone, melatonin controls 80 the sleep rhythm. At the same time, melatonin fulfills important functions as an antioxidant and in the down-regulation of many other biolo- gical processes. Infants and young children still produce large 0 amounts of melatonin, but older people produce less and less 0 1 2 4 6 8 10 12 Time in hours – resulting in sleep disorders and sleep deprivation in the el- derly.In view of the fact that melatonin is metabolized very quickly by the human body and its half-life is therefore no more than 40-60 minutes, it is understandable that supple-Fig.3/ CaffXtend: Better and healthier effects through continuous release® mentation becomes more effective to the extent that it is pos-over 12 hours. sible to provide the body with melatonin as required as so- called "long-acting melatonin". distributor for all Nutriventia products. Vivatis provides com- prehensive advice on the subject of “Slow/Modified Re- Nutriventia has developed Melatonin Sustained Release spe-lease” –for raw materials and,if required,also for cifically for this purpose. It is released in the body over thecorresponding finished products. course of 8 hours in such a way (see Fig. 1) that it not only makes it possible to fall asleep more quickly, but also enablesDiana Kalustova healthy sleep over the entire period, combined with a naturalManager for Scientific Business Development alternation of sleep phases. Vivatis Pharma GmbH lm/gn amsalP ni noitartnecnoC naeMtnerep ni saelelairotrevdA / lennoitcadér-ilbuP ceR642000