BONE MAINTENANCE Framroze and coll., 2016). In light of these encou- Closely related to joints problems, bone health is raging results, three product concepts are cur- one of the segments that makes wise use of ma- rently offered on the weight-loss and sports nutri- rine ingredients. Novastell has developed a range tion market with ProGo®, with the stated goal of of active ingredients extracted from herring roe overthrowing dairy proteins. The three targets are (Lecimarine®) known for its high content of DHA recovery, weight management and muscle mass. in phospholipid form. A preclinical study has re- Slimpro®, an active ingredient developed by the cently shown that an oil intake based on marine Compagnie des Pêches Saint-Malo fishing opera- phospholipids reduces bone resorption and in- tor, proved its effectiveness in overweight women: creases bone mineral density. DHA seems to be 3.5 kg weight loss in three months, out of which particularly active, unlike arachidonic acid, which 2.9 kg body fat (V. Nobile and coll., 2016). This in- leads to increased fragility. In this particular seg- gredient is a fully traceable protein hydrolysate ment, generic claims are supporting the sale of obtained from blue whiting, since the raw mate- active ingredients that are sources of calcium. rial is caught by the group. Preliminary processing Abyss Ingredients has developed Calcilyss®, a sar- takes place on board. Cholecystokinin (satiety dine scale powder and Phosphymer®, a white fish hormone) and glucagon-like peptide-1(GLP-1) bone powder. Their mineral (calcium and phos- levels increased in the group supplemented with phorus) content justifies their use for bone deve- the marine hydrolysate. lopment and maintenance with 3 to 5 g recom- mended per day. COGNITION AIMS HIGH Well known for its industrial expertise in ma- As illustrated by Mnemosyss®, a marine ingre- rine biomass and, in particular, in seaweeds dient targeting cerebral ageing and, in particular, through its fishing vessels and processing plant, memory disorders. Behind it, Abyss Ingredients, Nuwen (former Setalg, part of Roullier Group) Diana Petfood, Conserverie Chancerelle and the meets this demand with Algalithe. This powder LEMAR and NUTRINEURO laboratories, all of high in calcium comes from a fossilized red alga them partnered around a Brainbooster project. (Lithothamnion calcareum) that grows mainly in This latter marked “a milestone for the efficacy the seabed of the North Atlantic Ocean. Set up in tests and R&D of the company”, Claire Le Grand 2005, Nuwen henceforth focuses on building a re- says. Mathilde Chataigner was integrated into this putation in the field of nutraceuticals. Now ha- team through her CIFRE (Industrial agreements ving its own in-house staff dedicated to Research for training through research) thesis in order to & Development, the entity specialized in health see the project through its completion (ever since, nutrition aims to launch two novel ingredients in she has been appointed R&D Manager Abyss 2022. By working in close partnership and sharing Ingredients). The originality of Mnemosyss®, a knowledge, skills and a catchment area with the blue fish by-product hydrolysate, is that it consists Global Centre for Innovation of the group, Nuwen of low molecular weight peptides and omega-3s is expected to reach this new objective. (EPA and DHA). In aged mice receiving the ac- tive ingredient, memory deficits were successful- WEIGHT ACROSS ALL STAGES ly prevented in the short and long term. Brain in- Marine ingredients are proving increasingly flammation was also reduced, the basal balance more their preventive effect on the development being restored. Moreover, the response to stress of Type 2 diabetes and weight management. was improved. In light of these encouraging re- Among the latest evidence available, mice rende- sults3,4, the company will also launch clinical red obese by diet were supplemented during nine trials. Nearly 50 subjects with memory disorders weeks with fish extracts (cod, haddock, pollock) but no specific pathology will be monitored du- in powder form provided by the Norwegian com- ring three ? of supplementation with 4 capsules pany Seagarden. Glucose intolerance was impro- per day (that is 2.35 g of active ingredient per day). ved in these mice, regardless of the abdominal fat Please note that the study is being launched this built up. Some of them were supplemented with summer and the results are expected for 2023— fish powders, marine collagen (cod skin hydroly- 800 to 900 persons are to be recruited. During sate) and saw a modulation of their intestinal mi- the next Vitafoods, various concepts of products crobiome. Also in Norway, Hofseth BioCare de- formulated with Mnemosyss® will be introduced: veloped ProGo®, a salmon protein hydrolysate. gummies, but also sticks. If the current trends— A clinical study had reported a reduction of the naturalness, sustainability, local sourcing, and body mass index in subjects taking the hydroly- tangible evidence—are here to stay, Abyss sate (-5.9%). On the other hand, the placebo group Ingredients as well as the other players in the ma- supplemented with whey had put on weight (B. rine sector stand strong growth opportunities. •