Digestion seems to be the challenge of the century (or yet another one!). Above all, it is the segment ranked third in France in the sales of food supplements. More than one in two French people suffer from digestive disorders, but as significant as this target may be, it is nonetheless demanding. Let’s take a closer look at this major French nutraceutical market. Words have liberated themselves and currently it is no longer rude psychological well-being (Probi Digestis®). Similar results as con- to talk about transit problems, such as bloating, flatulence or ab- cerns the symptoms of depression in IBS patients were obtained dominal pain when conversing with someone else... For digestive with LactoSpore® (Bacillus coagulans MTCC 5856; Majeed, 2018), disorders, this is a newly gained freedom reflected by figures. In a probiotic stable at different temperatures (from ice to tea) and 2020, the sales in France of food supplements targeting digestion distributed by Becarre Natural. In patients suffering from IBD, tak- generated nearly €250 million, with a well-deserved position just ing LactoSpore® led to a significant improvement in abdominal behind stress/sleep and vitality segments. A slight decline (- 1.7%) pain and distension, and in intestinal transit. as compared to last year, of course, but a ranking in the system- And clinical data is all the more important when the target is rep- atic top three of distribution channels: pharmacies, super- and resented by children. Indeed, these latter represent an appreci- hypermarkets and organic stores (see Markets session in this is- able target for these food supplements as children are prone to sue / IQVIA, IRI, ©good.BioAnalytics). Many consumers intrinsi- digestive problems and parents prefer avoiding the use of drugs. cally link their digestive health to their general well-being. Aware Deerland Probiotics & Enzymes (Ireland) has shown that the2 that their immune potential is mainly stored in their belly, prior- strain Bacillus subtilis DE111® reduces the duration of vomiting ity is given to intestinal concerns. and constipation in young chil- But not in any way whatsoever! dren (2–6-year-olds) frequently Beyond trusting their own feel- developing gastrointestinal infec- ings, tangible scientific evidence « As a guiding light, tions. Better than drug treatment, is now considered essential; labo- health claims may be useful this is the challenge taken up by ratories’ commitments are strong- and some laboratories have fully Biosearch Life (Spain), which ly needed to motivate purchases tackled infantile colic by com- and, finally, practicality and pleas- understood it by adding zinc, paring the effect of the probiotic ure are what allows consumers to vitamin C and/or vitamin D strain B. breve CECT7263 (isolat- naturally integrate this well-being to their “digestive” formulation ed from breast milk) to the refer- gesture into their daily routine. to make claims on immunity. » ence drug prescribed in this case (simethicone). Not only was the3 SCIENCE, EVER-MORE reduction in infants’ crying time SCIENCE greater in the probiotic supple- Having experienced the san- ment group, but also the effect was itary crisis and persuaded that capsules are beneficial, the faster, the quality of night sleep was improved, and the mood of consumer of food supplements wants to go further in under- young parents was much more positive! standing their effectiveness, and, in particular, this link be- Regarding plants, the evidence is there as well. It is under the name tween digestion and immunity. Clever, but not enough, as the Mucosave™ FG that the Italian company Bionap offers a herbal active consumer wants more, and it is scientific data with“cliicllyna ingredient that improves gastrointestinal disorders such as heart- proven effectiveness” that he needs. As an obeying student, the burn and acid regurgitation by counteracting the gastroesophage- Swedish Probi AB substantiates its active ingredients with con- al reflux. Based on a combination of two extracts of Mediterranean sistent scientific dossiers, like in the case of its proprietary strainplants containing polysaccharides of prickle pear cladodes and Lactiplantibacillus plantarum 299v (LP299®). A brand new clinical phenols of olive leaves, this active ingredient has shown a strong study has confirmed the results already obtained in subjects suf-1 mucoadhesive activity (up to 60% of cell surface), higher than that fering from IBS and IBD* (no less than a dozen of trials conduct- of other bioadhesive polymers. In Spain, Euromed Group has de- ed at the initiative of the supplier), showing a reduction in diges- veloped Cynamed™, a water-soluble artichoke dry extract. Besides tive disorders while improving the subjects’ quality of life and their inulin, the extract contains phenolic and caffeoylquinic acids with ydutS esaC — reissoD NOITSEGID- 601 - noitsegiD -llew a devreseD ecalp eht no muidop