Stevanato group Les avantages des flacons en nest pour les produits biologiques lyophilisés La lyophilisation promet des conditions et des temps de stockage plus fiables lorsqu’il s’agit de produire des produits biologiques de grande valeur et à faible volume qui nécessitent des températures ultra-basses. Mais cela pose également de nouveaux défis aux fabricants de produits pharmaceutiques. The advantages of nested vials for freeze-dried biologics Freeze-drying holds the promise of more reliable storage conditions and times when it comes to the production of high-value, low-volume biologics that require ultra-low temperatures. But it also poses new challenges for pharmaceutical manufacturers. The lyophilization processsecondary drying (desorption). Theensures good heat transfer, which is consists of three steps – free-current process with bulk vials isconsidered essential. zing (ice formation), primarybased on direct contact between the drying (sublimation) andvials and the freeze-dryer shelf. ThisHowever, ready-to-fill containers 52The Pharmaceutical Post 19 / Juil let - 2024