Not only does this rotating handle ensure comfort of use,in a closed and antistatic environment. It also promotes but it also allows the spray to be firmly held in place forthe inhalation of the finest spray particles - which will an airtight seal and an upright position at all times. Otherbe able to reach the pulmonary alveoli - thereby limiting features that make it easier to use include its highly visiblethe inhalation of the large particles that tend to settle metering valve, which allows checking whether the patientin the throat and mouth cavity, which may lead to side is breathing properly and the treatment is being taken effects. “This chamber has been designed according to effectively. To minimise the inhalation effort, the largethe Canadian standard CAN CSA Z264.1-2, which is “Duck-Bill” Valve (the largest on the market) has been recognized as the standard for the development of this designed to maintain normal breathing. Of course, this type of medical device. According to a study carried device is compatible with all the sprays on the market thatout by the University of Parma, the overall performance can be quickly inserted and it is fully removable for easyof this chamber is better than that of inhalation cleaning. chambers existing on the market. As for the molecule most commonly proposed in asthma treatments (BDP/ Proven effectiveness Beclomethasone Dipropionate), it allows for a better inhalation of fine particles, which have been identified as But undoubtedly the most important point is that thanksthe most effective ones. We are proud of these results and to its original architecture, this inhalation chamber avoidsto see tour teams rewarded or their creatifvity,” Virginie the direct projection of the particles onto the mouth, Delay concludes. Marketed at the beginning of 2020, it is thereby offering a double benefit. It allows overcomingavailable in three models: for 0-2 year olds and 2-6 year the potential synchronization problems between sprayingolds with an adapted mask and for adults with a mask sold and breathing through the good treatment suspension separately. FOCUS appuyant et relâchant le bouton latéral(sumatriptan nasal powder) in the de dispositif. L’embout buccal flexibleUnited States, Canada and Mexico. This et l’embout nasal de forme asymétriquemigraine treatment is the first medication ONZETRA® ® font partie du mécanisme qui utilise lato be marketed with the Optinose device, XSAIL DE respiration expirée du patient pour scellera «bi-directional» exhalation delivery CURRAX PHARMACEUTICALS naturellement le palais mou et pour system (EDS) that uses the patient’s UTILISE LA TECHNOLOGIE faciliter l’administration de médicamentnatural breathing functions to help deliver D’OPTINOSE aux voiesnasales à travers l’embout nasalthe medication efficiently and effectively d’obturation. Après l’administrationbeyond the nasal valve into the deep, En septembre 2019, Optinose a annoncédu médicament, l’embout nasal est targeted areas of the nasal cavity. This un accord de licence avec Currax retiré du système et jeté. La technologieEDS has a flexible disposable mouthpiece Pharmaceuticals qui accorde à Currax lesd’Optinose fonctionne également pourand a sealing nose nozzle. Each nasal droits exclusifs sur certaines propriétésdes formulations liquides avec un flaconnozzle is pre-filled with a medication intellectuelles d’Optinose dans le butet une pompe de pulvérisation doseuse.capsule containing a dry powder decommercialiser Onzetra® ®Xsail D’autres médicaments sont en cours deformulation. The capsule is pierced by (poudre nasale de sumatriptan) aux développementtels que Xhance, un® pressing and releasing the side button of États-Unis, au Canada et au Mexique. corticoïde (propioniate de fluticasone)the device. The flexible mouthpiece and Ce traitement contre la migraine est lepour le traitement des polypes nasaux etthe asymmetrically shaped nasal nozzle premier médicament à être mis sur le OPN-300 (ocytocine), pour notamment leare part of the mechanism that uses the marché avec le dispositif d’Optinose, untraitement de troubles autistiques.patient’s exhaled breath to naturally seal système « bi-directionnel » de diffusion closed the soft palate and to facilitate par exhalation (EDS – exhalation delivery ONZETRA®XSAIL FROM® delivery of the medication to the nasal systems) qui utilise les fonctions naturelles passages through the sealing nosepiece. dela respiration du patient pour aider àCURRAX PHARMACEUTICALS After delivering the drug, the nosepiece is administrer efficacement et effectivement USESTHE OPTINOSE® removed from the system and discarded. le médicament au-delà de la valve nasale TECHNOLOGY The Optinose technology also works jusqu’aux zones profondes ciblées de for liquid formulations with a vial and la cavité nasale. Cet EDS possède un In September 2019, Optinose announcedmetering spray pump. Other drugs embout buccal flexible jetable et un a licensing agreement with Currax under development include Xhance®, a embout nasal étanche. Chaque embout Pharmaceuticals granting this lattercorticosteroid (fluticasone propioniate) nasal est pré-rempli par une capsule deexclusive rights over certain of itsfor the treatment of nasal polyps, and médicament contenant une formulation Optinose intellectual property for theOPN-300 (oxytocin) for the treatment of de poudre sèche. La capsule est percée enpurpose of marketing Onzetra® Xsail®autistic disorders, among others. January - 2020 / The Pharmaceutical Post 01 69 KCAP