20 KEY INGREDIENTS Visittheirbooth ENEFICIAL ROLE OF NATICOL,® NATURAL AND SPECIFIC TYPE 1 FISH COLLAGEN PEPTIDES, IN DIET- INDUCED OBESITY AND ASSOCIATED DISORDERS M odern lifestyle characterized ly, obesity is strongly associated with permanent lack of time with insulin resistance, which, results both in consumption of when coupled with relative in- a highly processed foods rich in sulin deficiency, leads to the de- fat, salt or/ and sugar and poor velopment of type 2 diabetes. physical activity which do not have any beneficial effects on As the incidence of diabetes is in- health: overweight/ obesity, hy- creasing worldwide and currently perglycemia, insulin-resistance. affects more than 194 million in- dividuals [1], it will become one of Obesity is defined as an abnor- the major public health concerns mal or excessive fat accumulation in the next decades. Among the that may impair health. This ex- different types of diabetes, type cess of adipose tissue results in 2 diabetes mellitus (T2DM) is a chronic low-grade inflammato- highly prevalent, accounting for ry state (macrophage infiltratioαn,TNF , IL-6,…) leadind to insulin about 90% of the total diabetic patients [2]. In T2DM, patients pathway alteration. Consequent- often face the problem of lack