14 MARKET The resulting two-carbon mole- tion rate of fatty acids in healthy cules are used as a substrate in humans.11 This process, by which the Krebs cycle and help to even- fatty acids are converted into a tually produce energy in the form usable form of energy, plays an im- of ATP (adenosine triphosphate). portant role in supporting weight management. In another separate This mechanism of action, confir- clinical trial, a significant increase med in clinical trials,6 7 makes in exhalation of 13 C-labeled car- L-Carnitine an ideal ingredient for bon dioxide was also recorded af- use in weight management sup- ter ten days of Carnipure L-Carni-® plements. For instance, a recent tine supplementation, indicating a meta-analysis, which included nine significant rise in beta-oxidation.12 clinical trials, showed that supple- mentation with L-Carnitine led InnovatIvedeLIvery to a significant decrease in both systems body weight and body mass index (BMI) compared to a placebo.8 In addition, studies in animals and Selecting the right dosage form clinical trials showed that L-Car- is crucial for the effective delive- nitine supplementation alone, or ry of weight management ingre- in combination with other amino dients. Convenient and easy-to- acids, resulted in an increase or swallow, capsules are one of the maintenance of lean muscle mass, most popular technologies for particularly after exercise. 9 10 such products, as they enable the delivery of a wide range of Manufactured by Lonza CH&N, the ingredients, including liquids, so- Carnipure brand is a high-quality® lids and semi-solids. Liquid ingre- grade of L-Carnitine ingredients. dients remain a popular choice for Bright white in color, Carnipure® supplement manufacturers in the L-Carnitine is extremely versatile weight management market. Such and can be used in a variety of die- formulations may offer increased tary supplement applications, from bioavailability, purity and differen- capsules and tablets, to functional tiation compared to traditional foods and beverages. For ins- dosage forms. However, formu- tance, Carnipure L-Carnitine has® lating with these ingredients can been found to increase the oxida- typically be difficult and present