NutraConnect KEY INGREDIENTS nistration of collagen in the knee ment in treatment was assessed of subjects with osteoarthritis de- with reduction in Western Ontario monstrated a significant local in- McMaster Universities (WOMAC). flammation decrease (increase in T Quality of life (QOL) scores and regs, IL-10 and decrease in IL-1β) short physical performance batte- and a mitigation in the symptoms ry (SPPB) scores from baseline to inherent to the pathology ³ (Furu- week 12 were also evaluated. Safety zawa-Carballeda et al., 2012). and tolerance were assessed. Similarly, oraladministration of womacsubscores- collagen hydrolyzates in mice with (painandphysical post-traumatic osteoarthritis inhi-bited synovialinflammation and Functionareimproved) induced cartilage regeneration 4 (Dar et al., 2016).In this double- blind randomized, against placebo study, WEISHARDT has assessed the potential effects of its specific fish collagen peptides (Naticol®) on knee osteoarthritis, after an oral intake of 10g/day for 8 and 12 weeks. naticol®clinically, provenbeneFits This study was carried out on 30 volunteers mean-aged 61 years old, randomized in two groups to receive at once a day 10g dose of specific fish collagen peptides (Na- ticol®) or the placebo for 12 weeks. As a primary objective, improve-