34 KEY INGREDIENTS PEPTAN IIm, HYDROLYZED in a recent set of in vivo studies. Its6 COLLAGEN TYPE II MATRIX efficacy was demonstrated in the DELIVERING MULTIPLE context of injury-related osteoar- JOINT HEALTH BENEFITS thritis,as well as a combined a mouse model of post-traumatic singlematrixingredient and obesity-induced osteoarthritis. withmultiplejointhealth In a model for post-traumatic beneFits osteoarthritis, joint injury induces Extracted from natural the loss of cartilage (matrix and sources, cells) and a strong local inflam- Peptan IIm is a unique hydrolyzed mation of the knee joint. Supple- cartilage matrix that contains hy- mentation with Peptan IIm at a low drolyzed collagen type II in the form dose clearly demonstrated the fol- of bioactive peptides and glycosa- lowing: minoglycans, so called GAGs. Its unique composition contains the • Protection of the cartilage from same matrix ingredients, found in degeneration (normalization of car- human cartilage as well. Its effects tilage area, blue bar) and promotion on users: Peptan lIm provides mul- of lubrication through the stimulation tiple joint health benefits, including of proteoglycan synthesis in chon- reduction of joint inflammation. drocytes (increase in % of active cells, blue bar). REDUCES PROVIDES INFLAMMATION CUSHIONING AND LUBRICATION HYDROLYZED IIm GAGs COLLAGEN TYPE II PROTECTS CARTILAGE peptan iimseFFectson’ jointhealthasdemons, - tratedinscientiFicstudies • Promotion of anti-inflammatory action in the knee joint (reducing local Peptan IIm has been shown to be expression of inflammation markers an effective joint health ingredient in the synovial membrane, blue bar).