NutraConnect KEY INGREDIENTS Consumers face a wide variety of discomfort and immobility. Lonza’s choices and expect optimal results UC-II®ingredient has been shown from the products they consume. to initiate cell-signaling cascades A survey commissioned by Lon- which use the body’s natural re- za and conducted by the Natural pair mechanisms in the joints, and Marketing Institute (NMI) looked therefore plays a role in supporting at the key drivers and concerns the rebuilding of this cartilage.4, 5 for3,000 supplement users across France, Germany and Italy. The ingredient is supported by evi- dence from a wide range of clinical The results highlighted the diffe- studies. For example, research re- rences between the age groups cently published in Osteoarthritis and regions, but despite these & Cartilage demonstrated that UC- nuances, safety and quality were II®undenatured type II collagen di- the top two overriding concerns minished deterioration of articular for consumers surveyed.3 With cartilage in a rat model of OA. that in mind,now – more than ever before – people are well-in- The dose of the UC-II® ingre- formed about the products they dient selected for the study re- purchase and their benefits. presents the clinically tested hu- Therefore,there is a growing man equivalent dose of 40 mg demand across the industry for per day. As this small size and manufacturers to demonstrate once-per-day frequency provi- product efficacy and innovation, des an efficacious dose, it may with ingredients that are backed improve consumer compliance. by strong scientific evidence. UC-II® undenatured type II colla- ® gen has also been shown to help One such ingredient is UC-II improve joint comfort, mobility and undenatured type II collagen. Col- flexibility in people with OA and6,7 lagen is one of the main compo- is statistically significantly more nents of our cartilage. Our body’s effective than the combination of natural ability to produce collagen glucosamine and chondroitin, as slows down as we get older, re- measured by the Western On- sulting in the degradation of carti- tario and McMaster Universities lage that can ultimately lead to joint Osteoarthritis Index (WOMAC).8