Recommendations influence of fasting on liver stiffness measurement (lsM) Before performing liver stiffness measurement using the fibroscan, it is now recommended to wait® at least 2, ideally 3 hours after a meal. • a clinical study demonstrated that food intake “significantly increases liver stiffness in a high proportion of patients with chronichepatitis C and on healthy controls, and suggest to perform measurements after fasting for at least 3 hours”. [1] • Similar results in cirrhotic patients, with marked increase of liver stiffness after a standard liquid meal ingestion. [2] • a study also reported “evidence of cofounding effect of the meal on the accuracy of stiffness measurements”, and suggest that a period of 120 minutes should be observed before the performance of FibroScan. [3]® bibliography: 1. Mederacke, I., et al., Food intake increases liver stiffness in patients with chronic or resolved hepatitis C virus infection. Liver International, 2009, 29(10): p.1500-6. 2. berzigotti, a., et al., Effect of meal ingestion on liver stiffness in patients with cirrhosis and partial hypertension. ploS One, 2013. 8(3): p. e58742. 3. arena, u., et al,Liver stiffness is influenced by a standardized meal in patients with chronic hcv hepatitis at different stages of fibrotic evolution. hepatology, 2013. in press. Our products are subject to regulatory requirements that vary from country to country and therefore may not be available for sale or distribution in all markets. This marketing material is not intended for uS audience. www.echosens.com - conTAcT@echosens.com flash this code ®®MTMT SEruTcIp LauTcarTnOc-nOn - GnE 610201 nacSOrbIF-OcEr - dEVrESEr SThGIr LLa SnESOhcE ThGIrypOc © ynapMOc SnESOhcE FO SkraMEdarT Era , nacSOrbIF , ,SnESOhcE - 58431 OSI - 9540