intervention humaine, ce qui permet de gagner du temps lors de la mise en place et de maintenir l’environnement déjà établi. L’industrie pharmaceutique impose des procédures opérationnelles strictes, telles que celles réglementées par les BPF et la FDA, pour garantir un envi- ronnement propre approprié. Cela a également une incidence sur la concep- tion d’un robot, qui est spécifiquement conçu pour éviter la dispersion des contaminants et dans lequel les surfaces rugueuses sont évitées, afin de faciliter un nettoyage adéquat. Le deuxième avantage cohérent de l’application de la robotique a été men- tionné plus haut : les changements auto- matiques des actions suite aux entrées du contexte vers le robot. Certains cap- teurs détectent les caractéristiques des flacons (capacité, dimensions, forme) et, par conséquent, permettent au robot d’adapter ses actions à l’outil utilisé, en Bras robotisé du RTDS2 de Steriline excluant les éléments non conformes. Robotic arm of Steriline’s RTDS2 process happens through UV-transpa- managed automatically with no human its actions to the tool used, excluding rent materials; it is limited by shadow intervention, resulting in time saved non-compliant elements. effects and does not penetrate through during the set-up and by maintaining the materials. already established environment. RTDS2 The pharmaceutical industry imposes The benefits of robotics strict operative procedures, such as the The Robotic Tub Decontamination Sys- ones regulated by GMP and the FDA, tem is a robot-controlled system which Robotics is a branch of engineering that to ensure an appropriate clean environ- uses pulsed light to decontaminate the improves operative flexibility compared ment. This also affects a robot’s design, tub surface. It works within an isolator with classic solutions at the cost of a which is specifically conceived to ensure system, completely sealed and airtight, lower production rate. no contaminant dispersion and in which and it delivers up to a 6-log reduction in An industrial robot is a completely pro- rugged surfaces are avoided, to facilitate bacterial concentration. grammable mechatronic component proper cleaning. RTDS2 is composed of 3 chambers: that moves within a defined area. It can The second consistent advantage of the an inlet chamber, a robot arm ope- potentially perform any needed action application of robotics was mentioned rated decontamination chamber and compatible with its morphology and, above: automatic changes in the actions an outlet chamber. The line includes a even after the first application, its pur- following inputs from the context to the laminar flow with 0.45 m/s airflow in pose can be changed just by editing its robot. Some sensors detect glassware every chamber and a difference of 2 Pa software, delivering greater flexibility features (capacity, dimensions, form) between chambers. at a lower cost. Product changes can be and, consequently, let the robot adapt The pulsed light system consists of 4 October - 2021 / The Pharmaceutical Post 08 53 RENROC TREPXE